Doctor Life InflaCell Defense - Turmeric, Ginger, Boswellia, 60 capsules
- cell protection
- proper cell division
- supporting the body in inflammatory conditions: Rheumatoid arthritis, rheumatoid arthritis, irritable bowel syndrome and others
InfaCell Defense is a patented formula of 3 clinically tested, highly concentrated extracts using the synergy effect of turmeric, frankincense - Boswellia and ginger, which were developed using the latest extraction technology and effective delivery of active substances.
InflaCell outperforms other turmeric extracts in total curcumin absorption, achieving the highest levels of free curcuminoids in the blood compared to other turmeric extracts, including liposomal turmeric or BXM-95, whose bioavailability was determined based on turmeric metabolites, which have no therapeutic properties.
Curcuminoids are compounds in curcumin that help inhibit inflammation, support the health of joints and all internal organs, regulate a healthy immune response to inflammatory factors, which in turn translates into heart health and provides strong protection against free radicals. It should be noted that the total amount of free curcuminoids provided by even 95% standardized turmeric extracts (also with the addition of piperine) is low.
We have spent many years searching for a better, highly bioavailable form of curcumin that provides maximum health benefits. To achieve this, technology was developed that protects curcuminoids during digestion and provides more free curcuminoids.
Curcumin has long been known to have poor bioavailability, requiring high doses to achieve desired blood levels. The new formula solves this problem as follows:
It is not the curcumin itself that provides the therapeutic effect, but the entire natural matrix of turmeric, ginger and frankincense present in InflaCell
Instead of standard extracts, our preparation uses two types of extraction: water and alcohol, which provides better bioavailability than ever thought thanks to the reconstruction of the full natural matrix of turmeric (CNTM) with active curcuminoids, ginger with gynerolarmy and boswellic acids from frankincense. Their potency is the synergy between the extracted active bodies and the added original compounds of these herbs, which are often removed during the extraction process. For example, different molecules of the turmeric matrix have different polarity, i.e. the distribution of electric charge within it, which affects their ability to bind. In other words, the polarity or arrangement of polar and non-polar particles of the full turmeric matrix is an important key factor for absorption. The intestinal lining has a polar structure, while curcuminoids have a non-polar structure, therefore the intestinal tissue rejects the active substance and is not absorbed into the bloodstream. For curcuminoids to effectively penetrate the intestines, the structure carrying the polar charge must be identical to the digestive system.
PNS biological delivery system
Thanks to an advanced process, the natural ingredients of turmeric are integrated into the system of polar and non-polar layers (PNS).
The process involves isolating curcumin and "translating" it between polar (carbohydrates, turmeric fiber and turmeric proteins) and non-polar (turmeric oil). Using PNS technology, curcuminoids are a non-polar charge covered in layers of proteins and water-soluble carbohydrates that also come from the whole turmeric root and create a polar structure that is able to penetrate the intestinal wall and deliver the active ingredient curcumin at maximum absorbency. PNS technology uses all the ingredients of turmeric and structures it in such a way that curcumin can be absorbed directly into target cells without being broken down in the digestive tract, which increases its bioavailability.
PNS technology helps inhibit conjugation
In the body, curcuminoid compounds undergo conjugation, a normal chemical reaction in which one compound attaches to another. This is problematic because bound curcuminoids (metabolites) do not necessarily provide the same health benefits as unbound ones (free curcuminoids).
Inflacel contains turmeric extract protects curcuminoids against conjugation by arranging them into polar and non-polar layers. Clinical and preclinical data show that this allows for 10 times greater bioavailability and more effective delivery of curcuminoids to tissues than in the case of standardized curcumin.
In a clinical study, five hours after consuming the preparation, over 70% of all curcuminoids were in free form in the plasma. This guarantees even more comprehensive support for the health of the entire body thanks to the use of our curcumin supplement.
The combination of these three extracts helps prevent chronic inflammation by beneficially modulating the activity of the following intercellular signaling pathways. They inhibit:
- enzymes: COX-1 and COX-2,
- 5-LOX enzyme,
- inducible nitric oxide (iNOS),
- IkappaB-alpha degradation,
- transcription of cell surface receptors for oxidized LDL cholesterol;
- stimulated increase in prostaglandin E2 (PGE2)
- have a strong antioxidant effect - they remove superoxide and hydroxyl radicals
they reduce lipid peroxidation, the early stages of the inflammatory cascade. How these natural ingredients work at the cellular level may seem biologically complicated, but it should be remembered that these are not synthetic compounds that are foreign to the body. Instead, they work with the body's own processes to help restore natural functions.
Health benefits of curcumin
Inhibits inflammatory factors – curcumin extract inhibits inflammatory factors, which supports the health of all organs in the body, including joints. To support the proper response of the immune system to inflammatory factors, curcumin also inhibits the metabolism of arachidonic acid and the activity of cyclooxygenase, lipoxygenase and pro-inflammatory cytokines.
Supports brain and immune system health – Curcumin extract inhibits inflammatory factors in the body, which supports immune system health. Curcumin may also benefit the brain and nervous system: research suggests that curcumin supports proper brain function and protects nerve cells.
Supports the digestive system, pancreas and joint health - curcumin supports proper intestinal function and joint health. It also helps maintain healthy, proper pancreatic function.
Protects cells against the harmful effects of free radicals - curcumin also protects cells against the harmful effects of free radicals. It also helps maintain healthy cholesterol levels in people who already have them in the normal range. It also supports the health of the cardiovascular system and many other organs
Health benefits of ginger
Ginger oil contains gingerols, shogaols and sesquiterpenes, which are powerful anti-inflammatory compounds. To illustrate a key element of their dramatically broader effectiveness in fighting inflammation, these natural ingredients provide powerful benefits that no currently available drug can provide - they block both COX and LOX enzymes, which in turn inhibits the synthesis of prostaglandin and leukotriene signaling molecules! This is crucial because scientists have found that agents that produce dual inhibition of COX and LOX enzymes potentially provide a "better therapeutic profile" and have almost no side effects compared to NSAIDs (i.e. nonsteroidal anti-inflammatory drugs).
Health benefits of frankincense - boswellia
Compounds contained in Boswellia extract have been shown to bind directly to the 5-LOX enzyme, which converts fatty acids into inflammatory factors such as leukotriene B4. Boswellia has an anti-inflammatory effect, which involves the regulation of pro-inflammatory cytokines and leukocyte infiltration, as well as an analgesic effect. Boswellic acid prevents the destruction of articular cartilage by inhibiting the degradation of glycosaminoglucans. All the above-mentioned properties have been confirmed in patients with knee osteoarthritis using preparations containing Boswellia serrata, in whom reduced knee pain, increased joint mobility and improved movement functions were observed.
Each vegetarian capsule contains 100 mg of 5-LOX inhibitor and is standardized to provide 30% active acetyl-keto-beta-boswellic acid (AKBA).
Dietary factors increase the incidence of 5-LOX
A typical diet increases 5-LOX levels. Foods high in omega-6 fatty acids, such as red meat, poultry, eggs and dairy products, along with high-glycemic carbohydrates, trigger the production of arachidonic acid. The body produces the 5-LOX enzyme in response to arachidonic acid
Advantages of 5-LOX modulation
5-LOX forms compounds such as leukotriene B4 from arachidonic acid. Leukotriene B4 inhibition helps maintain the health of joints, arteries and tissues. 5-LOX inhibition also helped support healthy cell division in preclinical models
Boswellia developed in the PNS system:
- absorbs 67% more than standard boswellia extract and is standardized to the active compound AKBA.
- Supports a healthy inflammatory response by inhibiting the 5-LOX enzyme
- supports joint health, artery health and healthy cell division.
- Patented formula of 3 clinically proven highly concentrated extracts of turmeric, boswellia and ginger
- InflaCell outperforms other turmeric formulas for the highest levels of curcuminoids in the blood ensuring optimal bioavailability
- Dual water and alcohol extraction achieves better bioavailability of turmeric, ginger and boswellia
- InflaCell is a natural alternative to non-steroidal anti-inflammatory drugs (NSAIDs) that double-blocks cox and lox enzymes
- Formulated with the PNS Biological Delivery System that utilizes the ordering of the plant's polar and non-polar layers to ultimately achieve the best bioavailability and anti-conjugation
Ingredients in a daily portion (1 capsule / 2 capsules)
Turmeric extract / 360 mg / 720 mg
Boswellia oleoresin / 100 mg / 200 mg
Ginger extract / 150 mg / 300 mg
Ingredients: turmeric rhizome extract (Curcuma longa), including: 50% curcuminoids; Indian frankincense oleoresin extract (Boswellia serrata), including: 30% 3-o-acetyl-11-keto-beta-boswellic acid; ginger rhizome extract (Zingiber officinale), including: 30% gingerols; (capsule shell (hydroxypropylmethylcellulose).
How to use: 1 capsule 2 times a day with food. Can be used with Doctor Life CELL DEFENSE, ONCO and UltraBran.
Producer: Doctor Life Sp. z o. o
Packaging: 60 capsules
Doctor Life's commitment is to improve the quality and length of life, which is why, with your health in mind, we create natural products from expensive and highest quality raw materials supported by scientific research.
Our inspiration is the scientist Linus Pauling, a double Nobel Prize winner. According to Pauling, to achieve perfect health, a person needs "the right amount of the right substances delivered to the right place in the body at the right time." Doctor Life's advanced recipes are developed with the greatest care by scientists, herbalists and pharmacists in strong, effective and safe quantities, and their purity is confirmed by an independent laboratory.