Aliness Beta Glukan 1.3-1.6 500mg 100 capsules

Food Supplement

• Beta Glucan 1,3-1,6 β-D
• 500 mg x 100 Vege capsules
• 100% Saccharomyces cerevisiae

1. What quality standards apply to the production of Yestimun® Beta-Glucan?

The Yestimun® Beta-Glucan production process complies with the following standards (certificates available on request):

• IFS
• BRC
• ISO 22000:2005
• Halal
• Kosher

2. Does Yestimun® Beta-Glucan contain additives?

Yestimun® Beta-Glucan is a completely natural and pure ingredient without any additives. It consists exclusively of brewer's yeast (100% Saccharomyces cerevisiae).

3. Is Yestimun® Beta-Glucan GMP certified?

We do not have a GMP certificate. However, we are very strict about the microbiological composition. We also analyze each batch for heavy metals.

4. Is Yestimun® Beta-Glucan safe?

Yestimun® Beta-Glucan is safe. It belongs to the food category because it is made from pure natural brewer's yeast. Safety has also been demonstrated in clinical studies on the effectiveness of Yestimun® Beta-Glucan. The ingredient can be consumed daily without any negative side effects [Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

5. Does Yestimun® Beta-Glucan have any side effects?

Clinical studies have shown that taking Yestimun® does not cause any side effects. All study participants rated the ingredient's tolerability as "very good" or "good"

[Auinger et al. (2013), Eur J Nutr Vol 52, Issue 8, pp. 19131918].

6. What are the functions of Yestimun® Beta-Glucan? How does the preparation work?

The yeast cell itself is covered with a layer of manno-oligosaccharides (MOS). During the production process, this layer is carefully removed so that the intestinal immune cells can recognize the three-dimensional matrix of beta-glucans. The immune system depends 70% on the gut. The special structure of β-1,3-1,6-glucan is recognized by cells in the small intestine, just like the pathogen. There is a functional, rapid and non-specific immune response that activates macrophages in Peyer's patches. Macrophages begin to destroy pathogens or activate other defense cells (B and T lymphocytes, dendritic cells).

7. What is the recommended daily dose (for adults)?

No studies have yet been conducted to determine the appropriate dose. The purpose of the research we conducted was to obtain a health claim (approximately 2 x 450 mg/day).

[Graubaum et al. (2012), FNS 3, 738–746] Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918]. [Rychlik et al. (2013), Acta Veterinaria Hungarica 61 (3), pp. 297-308].

8. What is the recommended daily dose for children?

For children, the daily dose may be lower than for adults. We have not conducted a clinical trial on children, but scientific analyzes show that 7 mg/kg body weight gives reliable results.

9. What time should Yestimun® Beta-Glucan be taken?

Yestimun® can be taken at any time of the day. A good solution is to take the preparation regularly at the same time - this way you can avoid missing a dose. Clinical trial participants took one capsule (450 mg) twice daily, e.g. for breakfast and dinner

[Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

10. Should Yestimun® Beta-Glucan be taken before, after or during a meal?

There are various theories regarding this issue. It is sometimes recommended to take beta-glucans some time before eating so that the structure of the molecule is better recognized as it passes through the digestive tract without interference from other molecules. Our clinical studies have shown that the effects also occur when the preparation is taken with a meal - not necessarily between or after meals. The preparation will be effective as an ingredient of dietary supplements and functional foods.

[Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, ed. 8, pp. 1913-1918].

11. Can Yestimun® Beta-Glucan be dissolved in liquids? Is the preparation soluble?

Yestimun® Beta-Glucan is dispersible but not soluble. Thanks to this, it can be added to liquid preparations, such as drinks or syrups, drinks, shakes

12. What about the purity of Yestimun® Beta-Glucan?

The purity of our beta-glucan is at least 85%. The production process includes various washing steps to obtain a pure beta-glucan structure and to remove other components such as mannan-oligosaccharides, fat and proteins.

13. Is Yestimun® Beta-Glucan suitable for vegans and/or vegetarians?

Yestimun® Beta-Glucan is a preparation suitable for vegans and vegetarians. It consists exclusively of brewer's yeast (100% Saccharomyces cerevisiae).

14. What is the vitamin content of Yestimun® Beta-Glucan?

We analyzed the vitamins contained in yeast from our local brewers, because it is a rich source of natural vitamins. Yestimun® Beta-Glucan is produced from brewer's yeast in a separation process that consists of at least three stages: Autolysis, then separation, first washing under slightly alkaline conditions at boiling point, then separation, second washing under neutral conditions at boiling point, and then separation. During these processes, all soluble substances (sugars, proteins, fat) are washed away, so we can assume that due to the long boiling time, most vitamins are washed out or deactivated.

15. Can Yestimun® Beta-Glucan cause allergies?

Yestimun® Beta-Glucan is produced from brewer's yeast. Yeast proteins may cause allergic reactions. During the production process, almost all proteins are removed, leaving only pure beta-glucan. Although beta-glucans come from brewer's yeast (Saccharomyces cerevisiae), they are a pure isolate and do not contain enough yeast proteins to cause an allergic reaction.

16. Does Yestimun® Beta-Glucan contain gluten?

Yestimun® Beta-Glucan was tested for gluten content and no trace of it was found. This is due to a combination of enzymatic and alkaline hydrolysis and several washing steps during the production process.

Brewer's yeast is grown on wort derived from barley. For brewer's yeast, levels of 200 ppm and above are typically used. Gluten is a protein complex based on several amino acids. During enzymatic autolysis (first stage), most of the gluten is hydrolyzed and individual amino acids do not cause an allergic reaction. The cell wall is then subjected to caustic treatment. Proteins, fats and mannan-oligosaccharides are hydrolyzed and washed out. The final step is rinsing, which finally removes the remaining fat, mannose and amino acids. Yestimun® Beta-Glucan becomes a highly purified glucan.

We have our own gluten analysis equipment, set to max. 20 ppm gluten. All analysis results showed that Yestimun® Beta-Glucan does not contain gluten.

17. Is there a health claim for Yestimun® Beta-Glucan?

Unfortunately, there are no official health claims yet for Yestimun® Beta-Glucan. Although all clinical results were positive, the EFSA (European Food Agency) invalidated the ability to officially communicate the properties of beta glucans. However, it has been proven in clinical trials that Yestimun® Beta-Glucan has a positive effect on the immune system.

[Graubaum et al. (2012), FNS 3, 738–746 / Auinger et al. (2013), Eur J Nutr Vol 52, Issue 8, pp. 1913-1918].

18. Is Yestimun® Beta-Glucan stable in an acidic environment?

Yestimun® Beta-Glucan was tested at various pH values ​​and temperatures. The results showed that there were no changes in the structure of the component. It is also stable in an acidic environment and can be added, for example, to acidic drinks.

19. Can beta glucan survive in the acidic environment of the stomach?

Beta-glucan is able to survive in stomach acid. Our research has shown that Yestimun® Beta-Glucan is truly acid-resistant. Therefore, the entire molecule can pass through the stomach and reach the intestine, where it is recognized by receptor cells [Rahar et al. (2011), J Adv Pharm Technol Res, Apr-Jun; 2(2): 94-103].

20. How to store Yestimun® Beta-Glucan correctly?

Yestimun® Beta-Glucan must be stored in a closed container, in a dry and cool place protected from light. Once the box is opened, it should be closed tightly and carefully so that the product maintains its quality.

21. What is the difference between yeast beta-glucan and oat beta-glucan?

Yeast and oat beta-glucan belong to the group of fibers, but they have a different structure and a completely different function. Oat beta-glucan has a β-1,3-1,4 connection type, while yeast beta-glucan - 1,3-1,6-β-D-glucan. The following numbers show the different types of connections.

22. What is the difference between brewer's and baker's yeast?

In breweries, brewer's yeast grows on naturally malted grains. These grains contain all the vitamins and trace elements needed for yeast growth. Unlike in the case of baker's yeast, no additional units are needed. Brewer's yeast requires a long maturation period during which it absorbs and accumulates additional minerals and vitamins from the grain. These unique features have made brewer's yeast a popular and effective dietary supplement.

Ingredients:  Yestimun® (Beer's yeast extract (Saccharomyces cervisiae) 85% beta 1,3-1,6 β-D glucan, capsule shell: (binding agent: hydroxypropyl methylcellulose).

Recommended daily dose:  1-2 capsules daily before a meal. Do not exceed the recommended daily dose.

Precautions:  The product cannot be used as a substitute for a varied diet. A balanced diet and a healthy lifestyle are the basis for the proper functioning of the body. Do not exceed the recommended daily dose.

Storage conditions:  Store at room temperature out of the reach of small children.

Packaging:  100 vege capsules

Expiry date:  08/2022