Aliness Methylo Folian 5-mthf 600 μg x 100 capsules

Ingredients	Daily portion (1 capsule)	RWS*%/daily portion
Glucosamine salt of (6S)-5-methyltetrahydrofolic acid including folate	1081  µg 600 µg	300%

*RWS: daily reference intake for adults. Reference intake for an average adult (8400 kJ/2000 kcal).

Ingredients : bulking agent: microcrystalline cellulose, glucosamine salt of (6S)-5-methyltetrahydrofolic acid, glazing agent (capsule shell): hydroxypropylmethylcellulose.

Recommended daily dose necessary to obtain the beneficial effect of the product:  1 capsule a day, during a meal.

 

The product cannot be used as a substitute for a varied diet.
A balanced diet and a healthy lifestyle are the basis for the proper functioning of the body. Do not exceed the recommended daily dose.

 

Storage conditions : Store at room temperature out of the reach of small children. Protect from moisture.

 

ACTION OF FOLATES:

• help in proper blood production
• help maintain proper homocysteine ​​metabolism
• help maintain proper psychological functions
• contribute to reducing the feeling of fatigue and weariness
• help in the proper functioning of the immune system
• they take part in the process of cell division
• help in the proper synthesis of amino acids
• contribute to the growth of maternal tissues during pregnancy

 

METHYLO FOLIAN 600 µg by ALINESS is a natural source of folate in the patented Quaterfolic® form . 

The term "Folic acid" includes all forms of folates. If the word "folate" sounds like "leaves" to you in English, it's no accident. The words share a common root (the Latin word folium, meaning "leaf"), which helps remind us that green plant foods can be one of the richest sources of folate.

 

Folates are susceptible to oxidation, rapidly lose activity in food and are largely, up to 90%, destroyed by cooking. 

 

Synthetic folic acid

Folic acid obtained from food must be metabolized to 5-methyltetrahydrofolate (5-MTHF) to achieve full metabolic effectiveness.

 

 

Folate in food is hydrolyzed to monoglutamate in the intestine before being absorbed by active transport through the intestinal mucosa. Therefore, before entering the bloodstream, the monoglutamate form is reduced to tetrahydrofolate (THF) and converted to methyl forms.

Folic acid, on the other hand, is first reduced to dihydrofolate by the enzyme dehydrofolate reductase (DHFR) and then to tetrahydrofolate. In humans, the intestine appears to have a very high capacity to convert reduced folate from food into 5-MTHF, but a limited capacity to reduce folate. In fact, it reaches the liver in an unmetabolized form.

 

 

RECOMMENDED CONSUMPTION

The intended use and levels of use of Quatrefolic® are the same as those of folic acid, expressed based on the "Recommended intake of folate for children and adults".

 

• help in proper blood production
• help maintain proper homocysteine ​​metabolism
• help maintain proper psychological functions
• contribute to reducing the feeling of fatigue and weariness
• help in the proper functioning of the immune system
• they take part in the process of cell division
• help in the proper synthesis of amino acids
• contribute to the growth of maternal tissues during pregnancy

 

Folate supplementation is recommended during pregnancy and lactation, for infants and small children, as well as the elderly.

 

PREGNANCY/LACTATION

An increased need for folate occurs during very active growth of the body's cells, such as during pregnancy and lactation.

Quatrefolic® as a source of (6S)-5-methyltetrahydrofolate (5-MTHF) may be particularly useful in providing a nutritionally active form of folate in the period before conception, during pregnancy and lactation.

Folate concentrations in breast milk are maintained at the expense of folate reserves in the mother's body.

A breastfeeding woman needs 128  μg of additional folate per day to replenish folate consumption.

5-MTHF has been shown to be effective and perhaps more effective than folic acid in maintaining erythrocyte folate concentrations during lactation.

Babies and children:

Folate is a critical nutrient when cell growth in the body is very active. It helps in the proper functioning of the immune system.

Adults:

Folate is involved in the production of key neurotransmitters in the brain, helping to maintain proper psychological functions.

Folate is a cofactor in many important biological reactions, and its deficiency can occur at all stages of life. Folate supplementation may improve the quality of life by reducing the feeling of fatigue and weariness

Elder people:

Folate deficiency occurs in approximately 30% of the elderly population.

Folate supplementation is important in older people because with age the level of homocysteine ​​in the blood increases and its metabolism depends on folate.

As part of the aging process, numerous physical and physiological changes occur.

Aging is associated with changes in the functioning of the gastrointestinal tract, which may possibly affect the absorption of various forms of folate. Supplementing folate with high bioavailability, especially in this age group, helps support proper psychological functions such as concentration, memory and learning.