Aliness Berberine Sulphate 99% 400 mg 60 capsules

Food supplement

High berberine content confirmed by the HPLC laboratory method. Standardized to 99% berberine.

Berberine  is a golden yellow alkaloid obtained from the roots and stems of Berbaris aristata or more commonly known as barberry. Berberine is also found in other plants such as Hydratis candensis (Goldenseal), Coptis chinensis (Coptis or Golden Thread), Berberis aquifolium (Oregon grape). These berberine-containing plants are used medicinally in virtually all traditional medical systems, and their history of use in Ayurvedic and Chinese medicine dates back at least 3,000 years.

Berberine, a quaternary alkaloid, is isolated as its hydrochloride (HCL) or sulfate salts. Berberine hydrochloride (HCL) is more popular on the market due to its price, but therefore its weaker effect. Berebrine sulfate is a less popular form (more bitter than HCL). The main difference in available berberines results from the method of isolating the active substance from the Berberis aristata plant.

Berberine hydrochloride and berberine sulfate – which form is better?

Both forms of berberine show the same activity in terms of the effects related to the properties of the main part of the molecule, i.e. berberine, because in the body, after dissolution, the molecule - both berberine sulfate and hydrochloride - dissociates into two independent parts: berberine - the main part of the compound showing activity and chloride or sulfate.

However, the advantage of sulfate over the hydrochloride form is that in berberine sulfate, in addition to the action of berberine itself, the sulfate residue detached from the molecule can be included in phase II detoxification reactions (i.e. conjugation or biotransformation) taking place in the liver. As a result of the conjugation reaction, xenobiotics (which are often toxic compounds) are metabolized in the liver to less toxic forms by attaching appropriate functional groups naturally occurring in the body to their molecule (including the sulfuric acid residue, i.e. sulfate). 

Berberine sulfate therefore provides additional "fuel" for the detoxification process. This is an additional positive effect of berberine sulfate, which is not demonstrated by the hydrochloride compound.

Ingredients:  Berberis root extract (Berberis Aristata) standardized to 99% berberine sulfate, capsule shell (binding substance: hydroxypropyl methylcellulose).

Recommended daily dose necessary to obtain a beneficial effect:  1 capsule during a meal. The product cannot be used as a substitute for a varied diet. A balanced diet and a healthy lifestyle are the basis for the proper functioning of the body. Do not exceed the recommended daily dose.

Storage conditions:  Store at room temperature out of the reach of small children. Protect from moisture.

Packaging:  60 vege capsules